Use of Gamma Radiation Sterilization for Single-Use Disposable Technologies

Symec Engineers in the biopharmaceutical industry are opting for gamma radiation sterilization facilities in India due to their safety time and affordability. This disposable system is used for processing the fluids, which range from the culture media, buffers, and additives to bulk intermediates and the final formulations.

The primary single-use technology for sterilization is gamma irradiation since plastics cannot be subjected to heat-based sterilization methods without affecting the mold, making it the ideal choice.

What Is Single-Use Disposable Technology?

Single-use disposable technology has been used in the biopharmaceutical industry for a long time. It is only at this time that this type of technology is being used in large-scale manufacturing. The driving force behind the wide adoption is the elimination and enhancement of cross-contamination, process efficiencies, sterility assurance, and cost-effectiveness.

This technology is generally manufactured through plastic polymers through injection molding, blow molding, and extruding. The applications consist of devices for producing sampling devices, aseptic connections, mixing devices, and product-holding bags.

What Is Gamma Radiation?

The utilization of ionizing radiation can be dated back to the development of X-rays in 1895, and gamma sterilization has been the method since the early 70s. in the 21st century, the use of gamma irradiation has boomed in the industry and replaced more established and expensive methods such as the ethylene oxide. It occurs from the gamma radiation used for sterilizing food items and the single-use technologies for the aseptic filling operations.

Process Of Gamma Radiation

The Gamma Radiation process is a type of ionization and is among the three types of natural radioactivity, and the other two are beta and alpha radiation. Gamma radiation is a type of electromagnetic ray like UV lights or X-rays. It offers the physical method of gamma irradiation plants in India and other food items as the rays go through the sterilized products. With this, it eliminates the bacteria where there is enough energy at the level of the molecule by exterminating the bacterial DNA.

Gamma radiation is also known as the cold process because the temperature of the material does not increase. The sterilization process does not depend on temperature, humidity, pressure, or vacuum. In other words, the whole process is best for materials not subjected to high-temperature sterilization.

The radiation strength dose is essential for gamma sterilization; it measures how much energy the material absorbs when exposed to the radiation source and the time. The radiation measurement is calculated in the KiloGrays in which the 1 gray absorbs one joule of radiation by 1kg of matter.

There are now many companies in India that are known for offering the best gamma irradiation services, which makes it necessary for some companies to opt for them to get rid of the bacteria within the consumables.

These are all the things that you should know about the single-use disposable for gamma irradiation. This method is preferred since it offers recommendations on the bioburden testing methods which can be used for validating radiation sterilization.

This articles guides user about the use of Gamma Radiation for Singe-use Disposable techniques.